Definition

Eosinophilic Esophagitis is a chronic inflammatory condition of the esophagus characterized by a high number of eosinophils in the esophageal tissue. Eosinophils are a type of white blood cell typically associated with allergic reactions or parasitic infections.

Pathogenesis

The exact cause of Eosinophilic Esophagitis remains unclear, but it is believed to be linked to allergic reactions. Evidence suggests that factors such as certain foods, airborne allergens, and genetic predispositions may play a role.

Diagnosis

The diagnosis of Eosinophilic Esophagitis is often made using endoscopy and esophageal biopsy. Physicians look for an abundance of eosinophils in the esophageal tissue and other signs of inflammation or damage.

Treatment

Treatment for Eosinophilic Esophagitis typically involves managing allergies and addressing inflammation. This can be achieved through dietary modifications, avoiding specific allergens, and using medications such as proton pump inhibitors or corticosteroids to control inflammation. In more severe cases, immunosuppressive drugs may be necessary. Endoscopic dilation may be required in cases of significant esophageal narrowing. Early diagnosis and ongoing monitoring are key to effectively managing the condition.